Drug-drug interactions for cannabinoids

A comprehensive list of drug-drug interactions for THC & CBD

Kocis and Vrana published an article in the peer-reviewed journal, Medical Cannabis and Cannabinoids on the 7th of July 2020 to provide a detailed and comprehensive drug-drug interaction list that is aligned with cannabinoid manufacturer prescribing information.

The cannabinoid drug-drug interaction information is listed in this article and online supplementary material as a PRECIPITANT (cannabinoid) medication that either INHIBITS/INDUCES the metabolism or competes for the same SUBSTRATE target (metabolic enzyme) of an OBJECT (OTHER) medication. 

In addition to a comprehensive list of drug-drug interactions, we also provide a list of 57 prescription medications displaying a narrow therapeutic index that are potentially impacted by concomitant cannabinoid use (whether through prescription use of cannabinoid medications or therapeutic/recreational use of cannabis and its extracts).


Cannabidiol Interactions with Medications, Illicit Substances, and Alcohol: a Comprehensive Review

Balachandran et al., published an article in the peer-reviewed journal, Journal of General Internal Medicine on the 29th of January 2021 to provide a systematic review and detailed list of drug-drug interactions between CBD and other therapeutic agents as well as addictive substances such as alcohol and tobacco.